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PubMedID Title Journal Author Re updated
28525741In?Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome.Mol Cell, 2017 May 18;66(4);488-502.e7,  0 2017/06/12
28394947
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Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2.PLoS One, 2017;12(4);e0175593, Okumura F, Joo-Okumura A, Nakatsukasa K, Kamura T 0 2017/04/17
27746020
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The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling.Mol Cell, 2016 Oct 20;64(2);251-266,  0 2016/11/11
27697924
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ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.J Cell Biol, 2016 Oct 3; [Epub ahead of print]Uematsu K, Okumura F, ..., Nakatsukasa K, Kamura T 0 2016/10/12
27090638
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Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.Mol Cell Biol, 2016 Jun 15;36(12);1803-17, Okumura F, Uematsu K, ..., Nakatsukasa K, Kamura T 0 2016/07/06
27050259
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Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8.Acta Crystallogr F Struct Biol Commun, 2016 Apr 1;72(Pt 4);269-75, Takagi K, Kim M, Sasakawa C, Mizushima T 1 2016/05/06
27091465
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Midori-ishi Cyan/monomeric Kusabira-Orange-based fluorescence resonance energy transfer assay for characterization of various E3 ligases.Genes Cells, 2016 Apr 18; [Epub ahead of print]Otsubo R, Kim M, Lee J, Sasakawa C 1 2016/05/06
26363554
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TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin.Cell Mol Life Sci, 2015 Sep 12; [Epub ahead of print]Suzuki M, Watanabe M, ..., Fukuda S, Hatakeyama S 0 2015/12/24
26578638
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The USP8 mutational status may predict drug susceptibility in corticotroph adenomas of Cushing's disease.Eur J Endocrinol, 2015 Nov 17; [Epub ahead of print]Hayashi K, Inoshita N, ..., Takeshita A, Yamada S 0 2015/11/23
25982115
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The Ubiquitin Ligase SCF(Ucc1) Acts as a Metabolic Switch for the Glyoxylate Cycle.Mol Cell, 2015 May 13; [Epub ahead of print]  0 2015/05/25
25905670
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The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ.Elife, 2015 Apr 23; [Epub ahead of print]Watanabe M, Takahashi H, ..., Tanaka K, Hatakeyama S 0 2015/05/06
25527407
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Ubiquitin acetylation inhibits polyubiquitin chain elongation.EMBO Rep, 2014 Dec 19; [Epub ahead of print]Ohtake F, Saeki Y, ..., Tanaka K, Kanno J 0 2015/01/03
25485838
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Mutations in the deubiquitinase gene USP8 cause Cushing's disease.Nat Genet, 2014 Dec 8; [Epub ahead of print]Reincke M, Sbiera S, ..., Fassnacht M, Komada M 0 2014/12/12
24784582
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Ubiquitin is phosphorylated by PINK1 to activate parkin.Nature, 2014 Apr 30; [Epub ahead of print]Koyano F, Okatsu K, ..., Tanaka K, Matsuda N 0 2014/05/04
24598877
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Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome.Nat Commun, 2014;3396, Pack CG, Yukii H, ..., Tanaka K, Saeki Y 0 2014/04/24
23898401
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Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4.Elife, 2013;e00953, Foresti O, Ruggiano A, ..., Ejsing CS, Carvalho P 0 2014/04/24
24469399
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Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex.Mol Cell Biol, 2014 Apr;34(7);1322-35, Fujita H, Rahighi S, ..., Wakatsuki S, Iwai K 0 2014/03/25
24634492
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IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex.J Immunol, 2014 Mar 14; [Epub ahead of print]Tamiya H, Terao M, ..., Yoshikawa H, Iwai K 0 2014/03/24
24461064
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Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.Genes Cells, 2014 Mar;19(3);254-272, Takiuchi T, Nakagawa T, ..., Kimura T, Iwai K 0 2014/03/24
24239290
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Autoadaptive ER-associated degradation defines a preemptive unfolded protein response pathway.Mol Cell, 2013 Dec 26;52(6);783-93,  0 2014/02/18
24075993
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The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells.Cell Rep, 2013 Oct 17;5(1);224-36,  0 2014/01/24
24357321
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CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.Science, 2013 Dec 20;342(6165);1518-21, Yu C, Zhang YL, ..., Sun QY, Fan HY 0 2014/01/17
23287719
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A strategy for modulation of enzymes in the ubiquitin system.Science, 2013 Feb 1;339(6119);590-5, Ernst A, Avvakumov G, ..., Dhe-Paganon S, Sidhu SS 0 2014/01/14
24158909Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.Science, 2013 Nov 22;342(6161);979-83, Tardiff DF, Jui NT, ..., Buchwald SL, Lindquist S 0 2014/01/03
24324262
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Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37.J Biol Chem, 2013 Dec 9; [Epub ahead of print]Tanno H, Shigematsu T, ..., Tanaka T, Komada M 0 2013/12/25
23991809
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Proteomics Analysis Reveals a Highly Heterogeneous Proteasome Composition and the Post-translational Regulation of Peptidase Activity under Pathogen Signaling in Plants.J Proteome Res, 2013 Sep 20; [Epub ahead of print]Sun HH, Fukao Y, ..., Sato T, Yamaguchi J 0 2013/10/01
23942237
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Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.EMBO J, 2013 Sep 11;32(18);2463-76, Sasaki Y, Sano S, ..., Kurosaki T, Iwai K 0 2013/09/15
23827681
連携完了
OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.Cell, 2013 Jul 3;154(1);169-84,  0 2013/08/02
23317502
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Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways.Mol Cell, 2013 Feb 7;49(3);487-98,  0 2013/07/05
23417015
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End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1.EMBO J, 2013 Mar 20;32(6);805-15, Lescasse R, Pobiega S, Callebaut I, Marcand S 0 2013/07/05
23726910
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The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification.Biochem Biophys Res Commun, 2013 Jun 28;436(2);223-9,  0 2013/07/05
23536702A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.Mol Biol Cell, 2013 Jun;24(11);1765-75, Nakatsukasa K, Brodsky JL, Kamura T 0 2013/07/04
23791384
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PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone.Cell, 2013 Jun 19; [Epub ahead of print]  0 2013/07/01
23754282
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Parkin catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.J Biol Chem, 2013 Jun 10; [Epub ahead of print]Iguchi M, Kujuro Y, ..., Tanaka K, Matsuda N 0 2013/06/30
23354051
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Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.Nature, 2013 Feb 21;494(7437);375-9, Song R, Peng W, ..., Cao CM, Xiao RP 0 2013/06/18
23453757
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Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins.Cell, 2013 Mar 28;153(1);206-15,  0 2013/05/10
23452853
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Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.Cell, 2013 Feb 28;152(5);1051-64,  0 2013/04/26
23453807
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The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO.Mol Cell, 2013 Mar 7;49(5);908-21,  0 2013/04/16
22895187
連携完了
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.Nature, 2012 Aug 30;488(7413);665-9, Koo BK, Spit M, ..., Maurice MM, Clevers H 0 2012/12/29
22575959
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ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.Nature, 2012 May 10;485(7397);195-200, Hao HX, Xie Y, ..., Serluca FC, Cong F 0 2012/12/29
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